Juvenile nasopharyngeal angiofibroma is a rare, highly vascular, and histologically benign tumor, generally observed in male adolescents. Aug 11, 2019 epidemiology juvenile nasopharyngeal angiofibromas. There are several distinct clinical forms of angiofibroma which share identical histopathology fibrous papule. Manejo multidisciplinario del angiofibroma juvenil. Variables analyzed included patient age, sex, symptoms, tumor stage, treatment, duration of surgery, volume of intraoperative bleeding, need for nasal packing after surgery, length of hospitalization, immediate and late complications, recurrence, and. A number of childhood conditions are characterized by angiofibromas, but the most common is tuberous sclerosis. This is a histologically benign lesion with very aggressive local behavior. We analyzed 20 patients with nasopharyngeal angiofibroma who underwent surgery in the otolaryngology service between 2004 and 2011. Clusters of rounded, epithelioid cells, often around vessels. Juvenile angiofibroma is a rare benign lesion originating from the pterygopalatine fossa with distinctive epidemiologic features and growth patterns. A metaanalysis of the different kinds of treatment used is reported. Definition of angiofibroma nci dictionary of cancer terms. The patients age and gender, as well as the geographic area.
The most common presenting symptom is painless nasal obstruction or epistaxis. Reddy ka, mendenhall wm, amdur rj, stringer sp, cassisi nj. Longterm results of radiation therapy for juvenile nasopharyngeal angiofibroma. Juvenile angiofibroma is a noncancerous growth that causes bleeding in the nose and sinuses. It is almost exclusicely encountered in adolescent males 1.
Asymptomatic, red to skin colored, dome shaped, firm papule usually on the nose or central face. Genetic evidence that juvenile nasopharyngeal angiofibroma is. Review article nasopharyngeal angiofibroma ashutosh hota. Pleomorphic angiofibroma is characterized by bizarre, stellate fibroblasts. Nasopharyngeal angiofibroma introduction juvenile nasopharyngeal angiofibroma jna is a benign, but locally aggressive and extremely vascular head and neck neoplasm, occurring almost exclusively in the nasopharynx of adolescent males. The tumors are fleshcolored to reddish and approximately 1 to 5 millimeters in diameter. Angiofibroma of soft tissue is a benign soft tissue tumor that is clinically and pathologically distinct from cellular angiofibroma see chapter 17 and nasopharyngeal angiofibroma see chapter 4.
Angiofibroma juvenil acta otorrinolaringologica espanola elsevier. Jan 09, 2015 manejo multidisciplinario del angiofibroma juvenil nasofaringeo. Endoscopic removal of a juvenile nasal angiofibroma. We offer a widget that you can add to your website to let users look up cancerrelated terms. Endoscopic surgery for juvenile nasopharyngeal angiofibroma where are. Angiofibroma juvenil acta otorrinolaringologica espanola. The tumor contains many blood vessels and spreads within the area in which it. Juvenile nasopharyngeal angiofibroma jna is a benign neoplasm of the nasopharynx. Angiofibroma, nasopharynx, epistaxis, embolization, endoscopic surgery. An epithelioid variant of angiofibroma consists of epithelioidtype cells with pink cytoplasm and prominent nucleoli. Angiofibroma juvenil nasofaringeo scielo cuba infomed. Angiofibroma definition of angiofibroma by medical. It shows very aggressive behavior due to local invasiveness and is associated with various symptoms.
The overlying epidermis is uninvolved but may be atrophic. Pdf it is presented a case of juvenile nasopharyngeal angiofibroma in a patient with this pathology, from the clicial practice no. Juvenile nasopharyngeal angiofibromas occur almost exclusively in males and usually in adolescence 15 years. Juvenile nasopharyngeal angiofibroma jna is a rare benign tumor arising predominantly in the nasopharynx of adolescent males. Angiofibromas are small, reddish brown or even fleshcolored, smooth, shiny, 0. Juvenile angiofibroma jna is a benign tumor that tends to bleed and occurs in the nasopharynx of prepubertal and adolescent males. Genetic evidence that juvenile nasopharyngeal angiofibroma. Angiofibromas are benign, vascular tumors that most often occur in young, adolescent males on the head and neck. Abstract it is presented a case of juvenile nasopharyngeal angiofibroma in a patient with this pathology, from the clicial practice no.
The patient in this photo has several facial angiofibromas. Tumor benigno no canceroso formado por vasos sanguineos y tejido fibroso conjuntivo. Adolescents and young adults between 14 and 25 years are affected, and there is a distinct male predominance. Manejo quirurgico del angiofibroma nasofaringeo juvenil.
Angiofibroma nasofaringeo juvenil, abordaje sublabial, cirugia endoscopica, endonasal, transpalatino. Differential diagnosis cellular angiofibroma surgical. Angiofibromas cause a domeshaped mass in the superficial dermis figure 1. Clear cell angiofibroma shows a proliferation of granular to foamy cells, resembling histiocytes. Ore 1, jose saavedra 1, ladislao pasache 1, roberto iwaki 1, francisco avello 1, johnny cardenas 1. Definition of angiofibroma national cancer institute. Epidemiology juvenile nasopharyngeal angiofibromas.
Juvenile nasopharyngeal angiofibroma jna is a rare locally invasive neoplasm composed of cavernous vascular channels set in an abundant myxoid stroma of fibroblasts and myofibroblasts. Angiofibroma of soft tissue occurs over a wide age range and affects females twice as frequently as males. The juvenile nasopharyngeal angiofibroma jna is a benign tumoral disease that may have a very aggressive behaviour, spreading from the nasopharynx to structures such as the cranial cavity, with a high morbidity. Aug 15, 2019 angiofibroma nasofaringeo pdf introduction. Juvenile nasopharyngeal angiofibroma originates in the sphenopalatine forame, causing epistaxes and nasal obstruction. Juvenile nasopharyngeal angiofibroma is a rare, highly luiz a cr, romualdo s lt, fava a s. Angiofibroma nasofaringeo juvenil ocronos revista medica. Juvenile nasopharyngeal angiofibroma jna is a rare and benign but locally aggressive fibrovascular tumor arising from the posterolateral wall of the. The nci dictionary of cancer terms features 8,568 terms related to cancer and medicine. Surgical treatment of juvenile nasopharyngeal angiofibroma.
Home acta otorrinolaringologica espanola comprar tratamiento quirurgico del angiofibroma nasofaringeo juvenil en pacientes pediatricos. Juvenile nasopharyngeal angiofibromas jna are a rare benign, but locally aggressive, vascular tumor. Manejo multidisciplinario del angiofibroma juvenil nasofaringeo. Angiofibroma is a pink, firm, 1 to 2mm domeshaped papule most commonly located over the nasal bridge and cheeks fig. Pdf on nov 27, 2014, maria herrero and others published angiofibroma nasofaringeo juvenil. Juvenile nasopharyngeal angiofibroma radiology reference. Histologically, angiofibromas are characterized by fibrosis of the dermis and blood vessels. Angiofibroma nasofaringeo juvenil experiencia en 10 anos. Angiofibroma nasofaringeo juvenil binipatia e higienismo. Nasal obstruction may become total, with adenoidtype speech. Although the use of nonsurgical therapies is described in the literature, surgery is currently considered the ideal treatment for.
154 867 335 880 654 1494 1086 1143 93 1490 368 2 1185 1475 486 410 1420 743 1053 26 1142 27 1560 10 132 1045 51 1039 656 826 805 1005 483 1447 798 1426 1348 310 908 618 11 130 948 461 993 225 1035 41 230 444